Highly lipophilic molecules. The meaning of HIGHLY is in or to a high place, level, or rank. WordReference Random House Learner's Dictionary of American English © 2025 high•ly /ˈhaɪli/ adv. a highly placed government advisor. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more. . in a high position: placed highly in class. Synonyms for HIGHLY: extremely, very, incredibly, terribly, too, so, badly, severely; Antonyms of HIGHLY: somewhat, slightly, little, nominally, negligibly, just, hardly, minimally HIGHLY meaning: 1. very, to a large degree, or at a high level: 2. generously: a highly paid consultant. Learn more. Highly definition: in or to a high degree; extremely. You use highly to indicate that someone has an important position in an organization or set of people. There are 11 meanings listed in OED's entry for the adverb highly, five of which are labelled obsolete. See ‘Meaning & use’ for definitions, usage, and quotation evidence. with great approbation or favour: we spoke highly of it. 2. in a way that shows admiration and respect: 3…. highly ranked soccer teams. Definition of highly adverb in Oxford Advanced Learner's Dictionary. 3. extremely: highly amusing; highly spiced food. HIGHLY definition: 1. How to use highly in a sentence. with high appreciation or praise: They spoke highly of you. 1. The meaning of HIGHLY is in or to a high place, level, or rank. See examples of HIGHLY used in a sentence. (intensifier): highly pleased; highly disappointed. suy1 mvkd s2eb uwhdyi 3zgq9 cn8fw g4nhg lduf pcq v6nj